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Anti-Thrombomodulin / CD141 Antibody, Sodium Azide Free
Catalog #: 188-11169-SAF
Mouse anti-Human Thrombomodulin Antibody / CD141 [Sodium Azide Free]
Product Description
Specifications
| Size | 100 µg |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Mouse |
| Accession Number | P07204 |
| Gene Id | 7056 |
| Gene Symbols | THBD,THRM |
| Protein Name / Synonyms | Thrombomodulin (TM) (Fetomodulin) (CD antigen CD141) |
| Immunogen | Human recombinant partial protein corresponding to amino acids 69-194 was used as the immunogen for this Thrombomodulin antibody. |
| Isotype | Kappa, IgG2b |
| Purity | Protein G affinity chromatography |
| Concentration (lot specific) | 1 mg/ml in 1X PBS, BSA free, sodium azide free |
| Recommended Applications | FACS: 0.5-1ug/10^6 cells in 0.1ml IF: 0.5-1ug/ml IHC (FFPE): 1-2ug/ml for 30 min at RT,ELISA: 2-4ug/ml, order the BSA-free formulation for coating Western Blotting: 0.5-1ug/ml |
| Domain / Region / Terminus | Cell surface, cytoplasmic |
| Shipping Type | Blue ice |
| Storage | ≤-20°C |
Description
Description
It recognizes a protein of 75kDa, identified as Thrombomodulin. Thrombomodulin is a transmembrane glycoprotein with natural anticoagulant properties. It is normally expressed by a restricted number of cells, such as endothelial and mesothelial cells. In addition, synovial lining and syncytio-trophoblasts of placenta also express thrombomodulin. This protein is present in almost all of benign vascular tumors and majority of malignant vascular tumors (Kaposi s sarcoma, angiosarcoma, and epithelioid hemangioendothelioma). Hence, anti-thrombomodulin serves as a sensitive marker for lymphatic endothelial cells and their tumors. Recently, thrombomodulin antibody has been used for mesothelial cells and malignant mesotheliomas.
Storage
Store the Thrombomodulin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Expiration:
12 months from the date of shipment when stored properly.