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ISO 13485:2016 cGMP
Anti-TK1 (162-185aa) Antibody
Catalog #: 130-10872-1000
Product Description
Specifications
| Size | 1000 µg |
| Estimated Lead Time | 1-2 business days |
| Species | Human |
| Host Species | Chicken |
| Accession Number | P04183 |
| Gene Id | 7083 |
| Gene Symbols | TK1 |
| Protein Name / Synonyms | TK1 (162-185aa) |
| Immunogen | Immunogen was synthetic peptide derived from TK1 (162-185aa):YTKRLGTEKEVEVIGGADKYHSVC. This antibody was produced from a chicken immunized with the immunogen conjugated with KLH. The IgY fraction was purified from collected egg followed by in-house affinity chromatography. |
| Immunogen Sequence | YTKRLGTEKEVEVIGGADKYHSVC |
| Recommended Applications | ELISA |
| Reconstitution | Product is supplied as a powder obtained from lyophilization of purified antibody in PBS without preservatives. Reconstitute the antibody with sterile water to a final concentration of 1 mg/ml. |
| Shipping Type | Ambient temperature |
| Storage | -20°C |
Description
Description
Thymidine kinases play a critical role in generating the DNA synthetic precursor deoxythymidine triphosphate (dTTP) by catalyzing the phosphotransfer of phosphate from ATP to deoxythymidine (dT) and thymidine (T) in the cell. There are two known thymidine kinases, cytoplasmic thymidine kinase 1 (TK1) and mitochondrial thymidine kinase 2 (TK2). Unlike TK2, which is not modulated by the cell cycle, TK1 expression and activity is regulated in a cell cycle-dependent manner, accumulating during G1-phase to peak levels in S-phase before being degraded prior to cell division.
Storage
The antibody is stable for at least 1 year from the date of receipt when stored at -20°C to -70°C. Reconstituted antibody can also be aliquotted and stored at 4°C for 1 month or at -20°C to -70°C in a manual defrost freezer for many months without detectable loss activity. Please avoid freeze-thaw cycles.
Expiration:
12 months from the date of shipment when stored properly.