Anti-TLR2 (Center) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	O60603
Gene Id	7097
Gene Symbols	TLR2
Protein Name / Synonyms	TLR2 (Center)
Clonality	Polyclonal
Preparation	This TLR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 281-310 amino acids from the Central region of human TLR2.
Concentration (lot specific)	0.430 mg/ml
Recommended Applications	Western Blotting
Research Area	Cancer, Inflammation
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB.

Specificity

Other Names

TLR2; TIL4; Toll-like receptor 2; Toll/interleukin-1 receptor-like protein 4; CD_antigen=CD282; Flags: Precursor

NCBI Accession #

NP_003255.2

Other Accession #

NP_003255.2

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

89838

Recommended Dilutions

WB: 1:1000

TLR2 Antibody (Center) (Cat# 102-12102) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the TLR2 antibody detected the TLR2 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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