3607 Parkway Ln Ste 200 Norcross, Georgia 30092
www.RayBiotech.com | info@raybiotech.com
770-729-2992 | +1-888-494-8555
ISO 13485:2016 cGMP
Anti-TLR7 Antibody
Catalog #: DS-MB-03427
Mouse Anti-Human TLR7
Product Description
Specifications
| Size | 0.1 mg |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Specificity | This product specifically recognizes human TLR7 (toll-like receptor 7), a 121 kDa type I transmembrane protein which belongs to the toll-like receptor (TLR) family, and is predominantly expressed in the spleen, lung and placenta. TLRs are highly conserved proteins which play a key role in activation of innate immunity, through the recognition of distinct molecular patterns expressed by infectious agents. TLR7 recognizes and interacts with single-stranded RNA (ssRNA) derived from viruses such as influenza , HIV-1 (human immunodeficiency virus type I) and Sendai, and some siRNAs, resulting in the activation of the MyD88/interleukin-1 receptor-associated kinase (IRAK) signaling pathway, and the production of proinflammatory signaling molecules. |
| Host Species | Mouse |
| Protein Name / Synonyms | TLR7 |
| Concentration (lot specific) | IgG concentration 1.0 mg/ml |
| Recommended Applications | ELISA (dilution: 1/1000, 1/2000), Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
This product detects a band of approximately 121 kDa in Ramos cell lysates.
Storage/Stability
Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Format
Supplied as:
Purified IgG - liquid
Formulation:
Phosphate buffered saline
Format Type:
Purified
Preparation
Immunogen:
Recombinant human TLR7 (amino acids 451-500) purified from Escherichia coli.
Preservative:
0.09% Sodium Azide (NaN3)
This product
Spleen cells from immunised Balb/c mice were fused with cells of the mouse SP2/0 myeloma cell line.
Expiration:
12 months from the date of shipment when stored properly.