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Anti-TLR7 (N-term) Antibody
Catalog #: 102-12777
Rabbit Anti-TLR7 (N-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse |
| Host Species | Rabbit |
| Accession Number | Q9NYK1 |
| Gene Id | 51284 |
| Gene Symbols | TLR7 |
| Protein Name / Synonyms | TLR7 (N-term) |
| Clonality | Polyclonal |
| Preparation | This TLR7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 98-128 amino acids from the N-terminal region of human TLR7. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Research Area | Inflammation |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. TLR7 is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8, on chromosome X.
Specificity
Other Names
TLR7; Toll-like receptor 7
NCBI Accession #
NP_057646.1
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
120922
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100
 | The anti-TLR7 Pab (Cat# 102-12777) is used in Western blot to detect TLR7 in mouse liver tissue lysate. |
 | TLR7 Antibody (C112) (Cat# 102-12777) western blot analysis in Ramos cell line lysates (35ug/lane).This demonstrates the TLR7 antibody detected the TLR7 protein (arrow). |
 | Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.