Anti-TMC6 (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q7Z403
Gene Id	11322
Gene Symbols	TMC6
Protein Name / Synonyms	TMC6 (N-term)
Clonality	Polyclonal
Preparation	This TMC6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 160-188 amino acids from the N-terminal region of human TMC6.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting
Research Area	Cancer
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Epidermodysplasia verruciformis (EV) is an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin. EV is caused by mutations in either of two adjacent genes located on chromosome 17q25.3. Both of these genes encode integral membrane proteins that localize to the endoplasmic reticulum and are predicted to form transmembrane channels. This gene encodes a transmembrane channel-like protein with 10 transmembrane domains and 2 leucine zipper motifs.

Specificity

Other Names

TMC6; EVER1; EVIN1; Transmembrane channel-like protein 6; Epidermodysplasia verruciformis protein 1; Protein LAK-4

NCBI Accession #

NP_001120670.1;NP_009198.4

Other Accession #

NP_009198.4; NP_001120670.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

90045

Recommended Dilutions

WB: 1:1000

TMC6 Antibody (N-term) (Cat# 102-12369) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the TMC6 antibody detected the TMC6 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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