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Anti-TNFAIP6 Antibody
Catalog #: 144-06419
TNFAIP6 Polyclonal Antibody
Product Description
Specifications
| Size | 20 µL, 100 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse, Rat |
| Host Species | Rabbit |
| Accession Number | P98066 |
| Gene Id | 7130 |
| Gene Symbols | TNFAIP6 |
| Protein Name / Synonyms | TNFAIP6, TSG-6, TSG6, TNF alpha induced protein 6 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purity | Affinity purification |
| Buffers | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
| Recommended Applications | Western Blotting, IHC |
| Research Area | Inflammation |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Background
The protein encoded by this gene is a secretory protein that contains a hyaluronan-binding domain, and thus is a member of the hyaluronan-binding protein family. The hyaluronan-binding domain is known to be involved in extracellular matrix stability and cell migration. This protein has been shown to form a stable complex with inter-alpha-inhibitor (I alpha I), and thus enhance the serine protease inhibitory activity of I alpha I, which is important in the protease network associated with inflammation. This gene can be induced by proinflammatory cytokines such as tumor necrosis factor alpha and interleukin-1. Enhanced levels of this protein are found in the synovial fluid of patients with osteoarthritis and rheumatoid arthritis.
Dilutions
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IHC 1:50 - 1:200
Format
Calculated MW
31kDa
Observed MW
41kDa
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 18-277 of human TNFAIP6 (NP_009046.2).
Modification
Unmodified
Storage
-20°C
Images
Western blot analysis of extracts of mouse brain, using TNFAIP6 Antibody (144-06419) at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Enhanced Kit.
Exposure time: 90s.
Immunohistochemistry of paraffin-embedded human stomach using TNFAIP6 antibody (144-06419) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded rat kidney using TNFAIP6 antibody (144-06419) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded mouse heart using TNFAIP6 antibody (144-06419) at dilution of 1:100 (40x lens).
Expiration:
12 months from the date of shipment when stored properly.