Anti-TNFSF14 Antibody

Product Description

Specifications

Size	20 µL, 100 µL
Estimated Lead Time	1-2 weeks
Species	Human, Mouse, Rat
Host Species	Rabbit
Accession Number	O43557
Gene Id	8740
Gene Symbols	TNFSF14
Protein Name / Synonyms	TNFSF14, CD258, HVEML, LIGHT, LTg, TNF superfamily member 14
Clonality	Polyclonal
Isotype	IgG
Purity	Affinity purification
Buffers	PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Recommended Applications	Western Blotting
Research Area	Inflammation
Shipping Type	Blue ice
Storage	-20°C

Description

Background

The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF14, which is a member of the tumor necrosis factor receptor superfamily, and which is also known as a herpesvirus entry mediator (HVEM). This protein may function as a costimulatory factor for the activation of lymphoid cells and as a deterrent to infection by herpesvirus. This protein has been shown to stimulate the proliferation of T cells, and trigger apoptosis of various tumor cells. This protein is also reported to prevent tumor necrosis factor alpha mediated apoptosis in primary hepatocyte. Two alternatively spliced transcript variant encoding distinct isoforms have been reported.

Dilutions

WB 1:1000 - 1:2000

Format

Calculated MW

22kDa/26kDa

Observed MW

30kDa

Immunogen

Recombinant protein of human TNFSF14

Modification

Unmodified

Storage

-20°C

Images

Western blot analysis of extracts of various cell lines, using TNFSF14 antibody (144-02002) at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 5s.
Western blot - TNFSF14 antibody (144-02002)

Expiration:

12 months from the date of shipment when stored properly.

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