Anti-TRAF3 Antibody

Product Description

Specifications

Size	20 µL, 100 µL
Estimated Lead Time	1-2 weeks
Species	Human, Mouse, Rat
Host Species	Rabbit
Accession Number	Q13114
Gene Id	7187
Gene Symbols	TRAF3
Protein Name / Synonyms	TRAF3, CAP-1, CAP1, CD40bp, CRAF1, IIAE5, LAP1, TNF receptor-associated factor 3
Clonality	Polyclonal
Isotype	IgG
Purity	Affinity purification
Buffers	PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Recommended Applications	Western Blotting, IF
Research Area	Cancer, Inflammation
Shipping Type	Blue ice
Storage	-20°C

Description

Background

The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF receptor (TNFR) superfamily. This protein participates in the signal transduction of CD40, a TNFR family member important for the activation of the immune response. This protein is found to be a critical component of the lymphotoxin-beta receptor (LTbetaR) signaling complex, which induces NF-kappaB activation and cell death initiated by LTbeta ligation. Epstein-Barr virus encoded latent infection membrane protein-1 (LMP1) can interact with this and several other members of the TRAF family, which may be essential for the oncogenic effects of LMP1. Several alternatively spliced transcript variants encoding three distinct isoforms have been reported.

Dilutions

WB 1:500 - 1:2000
IF 1:50 - 1:200

Format

Calculated MW

55kDa/64kDa

Observed MW

Refer to figures

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human TRAF3 (NP_003291.2).

Modification

Unmodified

Storage

-20°C

Images

Immunofluorescence analysis of U2OS cells using TRAF3 antibody (144-60917) at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunofluorescence - TRAF3 Polyclonal Antibody (144-60917)

Expiration:

12 months from the date of shipment when stored properly.

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