Anti-TREX1 Antibody

Product Description

Specifications

Size	20 µL, 100 µL
Estimated Lead Time	1-2 weeks
Species	Human, Mouse, Rat
Host Species	Rabbit
Accession Number	Q9NSU2
Gene Id	11277
Gene Symbols	TREX1
Protein Name / Synonyms	TREX1, AGS1, CRV, DRN3, HERNS, three-prime repair exonuclease 1
Clonality	Polyclonal
Isotype	IgG
Purity	Affinity purification
Buffers	PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Recommended Applications	Western Blotting, IF
Research Area	Cardiovascular Disease, Cancer, Inflammation, Autoimmune Disease
Shipping Type	Blue ice
Storage	-20°C

Description

Background

This gene encodes a nuclear protein with 3' exonuclease activity. The encoded protein may play a role in DNA repair and serve as a proofreading function for DNA polymerase. Mutations in this gene result in Aicardi-Goutieres syndrome, chilblain lupus, Cree encephalitis, and other diseases of the immune system. Alternative splicing results in multiple transcript variants.

Dilutions

WB 1:500 - 1:2000
IF 1:50 - 1:200

Format

Calculated MW

32kDa/33kDa/38kDa

Observed MW

37kDa

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human TREX1 (NP_057465.1).

Modification

Unmodified

Storage

-20°C

Images

Western blot analysis of extracts of various cell lines, using TREX1 antibody (144-06778) at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Enhanced Kit.
Exposure time: 90s.
Western blot - TREX1 Polyclonal Antibody (144-06778)

Immunofluorescence analysis of A549 cells using TREX1 antibody (144-06778). Blue: DAPI for nuclear staining.
Immunofluorescence - TREX1 Polyclonal Antibody (144-06778)

Immunofluorescence analysis of HeLa cells using TREX1 antibody (144-06778).
Immunofluorescence - TREX1 Polyclonal Antibody (144-06778)

Expiration:

12 months from the date of shipment when stored properly.

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