Anti-TRHR (Center) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P34981
Gene Id	7201
Gene Symbols	TRHR
Protein Name / Synonyms	TRHR (Center)
Clonality	Polyclonal
Preparation	This TRHR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 209-238 amino acids from the Central region of human TRHR.
Concentration (lot specific)	0.350 mg/ml
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Thyrotropin-releasing hormone (TRH; MIM 275120), a small neuropeptide, is widely distributed throughout the central and peripheral nervous system as well as in extraneural tissues. The peptide is synthesized in the hypothalamus and transported by the portal vascular system to the anterior pituitary where it acts on thyrotropic and lactotropic cells to promote secretion of TSH and prolactin, respectively. Thyrotropin-releasing hormone receptor is a G protein-coupled receptor that activates the inositol phospholipid-calcium-protein kinase C transduction pathway upon the binding of TRH. The TRHR gene is expressed in the thyrotrope cells of the anterior pituitary.

Specificity

Predicted Reactivity

Rat

Other Names

TRHR; Thyrotropin-releasing hormone receptor; Thyroliberin receptor

NCBI Accession #

NP_003292.1

Other Accession #

Q01717; NP_003292.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

45085

Recommended Dilutions

WB: 1:1000

TRHR Antibody (Center) (Cat# 102-13817) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the TRHR Antibody detected the TRHR protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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