Anti-TRIB2 (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q92519\|Q8K4K3\|Q5GLH2\|NP_067675
Gene Id	28951
Gene Symbols	TRIB2
Protein Name / Synonyms	Tribbles homolog 2, TRB-2, TRIB2 (HGNC:30809)
Clonality	Polyclonal
Clone	RB9215
Isotype	Kappa, Rabbit
Recommended Applications	Western Blotting, IHC-P, FC
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

TRIB2 is one of three members of the Tribbles family. The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. The Tribbles proteins interact and modulate the activity of signal transduction pathways in a number of physiological and pathological processes. This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin. It has been identified as a protein up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C/EBPalpha (CCAAT/enhancer-binding protein alpha) and causes acute myelogenous leukemia.

Other Information

NCBI Accession #

NP_067675.1

Antigen Type

Synthetic Peptide

Format

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Calculated Molecular Weight (Da)

38801

Antigen Source

Human

Images

WB (1:1000)

Western blot analysis of TRIB2 (arrow) using rabbit polyclonal TRIB2 N-term (Cat. #102-27631). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the TRIB2 gene (Lane 2) .

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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