Anti-TRIM23 (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P36406
Gene Id	373
Gene Symbols	TRIM23
Protein Name / Synonyms	TRIM23 (N-term)
Clonality	Polyclonal
Preparation	This TRIM23 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-175 amino acids from the N-terminal region of human TRIM23.
Concentration (lot specific)	0.410 mg/ml
Recommended Applications	Western Blotting, IHC-P
Research Area	Autophagy
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein is also a member of the ADP ribosylation factor family of guanine nucleotide-binding family of proteins. Its carboxy terminus contains an ADP-ribosylation factor domain and a guanine nucleotide binding site, while the amino terminus contains a GTPase activating protein domain which acts on the guanine nucleotide binding site. The protein localizes to lysosomes and the Golgi apparatus. It plays a role in the formation of intracellular transport vesicles, their movement from one compartment to another, and phopholipase D activation. Three alternatively spliced transcript variants for this gene have been described.

Specificity

Predicted Reactivity

Mouse, Rat

Other Names

TRIM23; ARD1; ARFD1; RNF46; E3 ubiquitin-protein ligase TRIM23; ADP-ribosylation factor domain-containing protein 1; GTP-binding protein ARD-1; RING finger protein 46; Tripartite motif-containing protein 23

NCBI Accession #

NP_001647.1;NP_150230.1;NP_150231.1

Other Accession #

P36407; Q8BGX0; NP_150230.1; NP_001647.1; NP_150231.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

64067

Recommended Dilutions

WB: 1:1000; IHC: 1:10-50

	TRIM23 Antibody (N-term) (Cat# 102-12083) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the TRIM23 antibody detected the TRIM23 protein (arrow).
	TRIM23 Antibody (N-term) (Cat# 102-12083)immunohistochemistry analysis in formalin fixed and paraffin embedded human thyroid tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TRIM23 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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