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Anti-TSG101 (N-term) Antibody
Catalog #: 102-24675
Rabbit Anti-TSG101 (N-term) Antibody, 400 µl
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse |
| Host Species | Rabbit |
| Accession Number | Q99816|NP_006283 |
| Gene Id | 7251 |
| Gene Symbols | TSG101 |
| Protein Name / Synonyms | Tumor susceptibility gene 101 protein, ESCRT-I complex subunit TSG101, TSG101 |
| Clonality | Polyclonal |
| Clone | RB04442 |
| Isotype | Kappa, Rabbit |
| Recommended Applications | Western Blotting, IHC-P |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
TSG101 belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression.
Other Information
NCBI Accession #
NP_006283.1
Antigen Type
Synthetic Peptide
Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Calculated Molecular Weight (Da)
43944
Antigen Source
Human
Images
WB (1:1000)
The anti-TSG101 Pab (Cat. #102-24675) is used in Western blot to detect TSG101 in mouse kidney tissue lysate.
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.