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Anti-UBE2L3 (N-term) Antibody
Catalog #: 102-14971
Rabbit Anti-Human UBE2L3 (N-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P68036 |
| Gene Id | 7332 |
| Gene Symbols | UBE2L3 |
| Protein Name / Synonyms | UBE2L3 (N-term) |
| Clonality | Polyclonal |
| Preparation | This UBE2L3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human UBE2L3. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). UBE2L3 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro.
Specificity
Predicted Reactivity
Mouse, Bovine
Other Names
UBE2L3; UBCE7; UBCH7; Ubiquitin-conjugating enzyme E2 L3; L-UBC; UbcH7; Ubiquitin carrier protein L3; Ubiquitin-conjugating enzyme E2-F1; Ubiquitin-protein ligase L3
NCBI Accession #
NP_001243284.1;NP_001243285.1;NP_003338.1
Other Accession #
P68037; Q3MHP1; NP_003338
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
17862
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100
 | Western blot analysis of UBE2L3 Antibody (N-term) (Cat# 102-14971) in Ramos cell line lysates (35ug/lane). UBE2L3 (arrow) was detected using the purified Pab. |
 | Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.