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ISO 13485:2016 cGMP
Anti-UCH-L1 Antibody
Catalog #: 130-10758
Product Description
Specifications
| Size | 20 µg, 100 µg, 200 µg |
| Estimated Lead Time | 1-2 business days |
| Species | Human |
| Host Species | Mouse |
| Accession Number | P09936 |
| Gene Id | 7345 |
| Gene Symbols | UCHL1 |
| Protein Name / Synonyms | UCH-L1 |
| Clonality | Monoclonal |
| Clone | 4H3-A6-G1-F7-E5 |
| Immunogen | Immunogen was recombinant protein human UCH-L1. This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with the immunogen. The IgG fraction of tissue culture supernatant was purified by Protein G/A affinity chromatography. |
| Recommended Applications | ELISA (recommended work dilution = 1:40, 000) |
| Reconstitution | Product is supplied as a powder obtained from lyophilization of purified antibody in 1 x PBS. Reconstitute the antibody with sterile water to a final concentration of 1 mg/ml. |
| Research Area | Autophagy |
| Shipping Type | Ambient temperature |
| Storage | -20°C |
Description
Description
UCH-L1 (ubiquitin carboxyterminal hydrolase isozyme 1; also PGP9.5) is a 24-27 kDa member of the peptidase C12 family of enzymes. It shows restricted expression, being found in neurons and oocytes. UCH-L1 has dual enzymatic activity. As a monomer, it is a ubiquitin hydrolase that removes ubiquitin from modified proteins; as a homodimer, it acts as a ligase that creates ubiquitin dimers. In neurons, UCH-L1 s most important role appears to be that of generating free ubiquitin.
Storage
The antibody is stable for at least 1 year from the date of receipt when stored at -20°C to -70°C. Reconstituted antibody can also be aliquotted and stored at 4°C for 1 month or at -20°C to -70°C in a manual defrost freezer for many months without detectable loss activity. Please avoid freeze-thaw cycles.
Expiration:
12 months from the date of shipment when stored properly.