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Anti-UchL1 Antibody, Sodium Azide Free
Catalog #: 188-11593-SAF
Mouse anti-Human/Cow/Dog/Guinea Pig//Mouse/Pig/Rabbit/Rat/Sheep/Zebrafish UchL1 Antibody [Sodium Azide Free]
Product Description
Specifications
| Size | 100 µg |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Specificity | Other species not known |
| Host Species | Mouse |
| Accession Number | P09936 |
| Gene Id | 7345 |
| Gene Symbols | UCHL1 |
| Protein Name / Synonyms | Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1) (EC 3.4.19.12) (EC 6.-.-.-) (Neuron cytoplasmic protein 9.5) (PGP 9.5) (PGP9.5) (Ubiquitin thioesterase L1) |
| Immunogen | Native UchL1/PGP9.5 protein isolated from human brain was used as the immunogen for this anti-UchL1 antibody. |
| Isotype | Kappa, IgG2a |
| Purity | Protein G affinity chromatography |
| Concentration (lot specific) | 1 mg/ml in 1X PBS, BSA free, sodium azide free |
| Recommended Applications | Western blot: 0.5-1ug/ml Immunofluorescence: 1-2ug/ml |
| Domain / Region / Terminus | Cytoplasmic. Endoplasmic Reticulum membrane |
| Research Area | Autophagy |
| Shipping Type | Blue ice |
| Storage | ≤-20°C |
Description
Description
This mAb reacts with a protein of 20-30kDa, identified as PGP9.5, also known as ubiquitin carboxyl-terminal hydrolase-1 (UchL1). Initially, UchL1 expression in normal tissues was reported in neurons and neuroendocrine cells but later it was found in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. Furthermore, immunostaining for UchL1 has been shown in a wide variety of mesenchymal neoplasms as well. A mutation in the gene is believed to cause a form of Parkinson's disease.
Storage
Store the anti-UchL1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Expiration:
12 months from the date of shipment when stored properly.