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Anti-UPF2 (Center) Antibody
Catalog #: 102-20580
Rabbit Anti-UPF2 (Center) Antibody, 400 µl
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q9HAU5|NP_056357.1 |
| Gene Id | 26019 |
| Gene Symbols | UPF2 |
| Protein Name / Synonyms | Regulator of nonsense transcripts 2, Nonsense mRNA reducing factor 2, Up-frameshift suppressor 2 homolog, hUpf2, UPF2, KIAA1408, RENT2 |
| Clonality | Polyclonal |
| Clone | RB21963 |
| Isotype | Kappa, Rabbit |
| Recommended Applications | Western Blotting, FC |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
UPF2 is a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located in the perinuclear area. It interacts with translation release factors and the proteins that are functional homologs of yeast Upf1p and Upf3p.
Other Information
Antigen Type
Synthetic Peptide
Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Calculated Molecular Weight (Da)
147810
Expiration:
12 months from the date of shipment when stored properly.