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Anti-UVRAG (Center) Antibody
Catalog #: 102-23227
Rabbit Anti-UVRAG (Center) Antibody, 400 µl
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse |
| Host Species | Rabbit |
| Accession Number | Q9P2Y5 |
| Gene Id | 7405 |
| Gene Symbols | UVRAG |
| Protein Name / Synonyms | UV radiation resistance-associated gene protein, p63, UVRAG |
| Clonality | Polyclonal |
| Clone | RB10847 |
| Isotype | Kappa, Rabbit |
| Recommended Applications | Western Blotting, IHC-P |
| Research Area | Autophagy |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
UVRAG complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer.
Other Information
NCBI Accession #
NP_003360.2
Antigen Type
Synthetic Peptide
Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Calculated Molecular Weight (Da)
78151
Antigen Source
Human
Images
WB (1:1000)
Western blot analysis of anti-hUVRAG (Center) Pab (RB10847) in mouse heart tissue lysates. hUVRAG (Center)(arrow) was detected using the purified Pab.
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.