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Anti-VASP (C-term) Antibody
Catalog #: 102-12250
Rabbit Anti-Human VASP (C-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P50552 |
| Gene Id | 7408 |
| Gene Symbols | VASP |
| Protein Name / Synonyms | VASP (C-term) |
| Clonality | Polyclonal |
| Preparation | This VASP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 267-296 amino acids from the C-terminal region of human VASP. |
| Concentration (lot specific) | 0.500 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG.
Specificity
Other Names
VASP; Vasodilator-stimulated phosphoprotein
NCBI Accession #
NP_003361.1
Other Accession #
NP_003361.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
39830
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50
 | VASP Antibody (C-term) (Cat# 102-12250) western blot analysis in HUVEC,THP-1 cell line lysates (35ug/lane).This demonstrates the VASP antibody detected the VASP protein (arrow). |
 | VASP Antibody (C-term) (Cat# 102-12250)immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsil tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of VASP Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.