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Anti-VEGF Antibody, Sodium Azide Free
Catalog #: 188-10742-SAF
Mouse anti-Human/Mouse/Rat/Rabbit/Dog VEGF Antibody [Sodium Azide Free]
Product Description
Specifications
| Size | 100 µg |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Specificity | Other species not tested. |
| Host Species | Mouse |
| Accession Number | P15692 |
| Gene Id | 7422 |
| Gene Symbols | VEGFA,VEGF |
| Protein Name / Synonyms | Vascular endothelial growth factor A (VEGF-A) (Vascular permeability factor) (VPF) |
| Immunogen | Human recombinant protein was used as the immunogen for the VEGF antibody. |
| Isotype | Kappa, IgG1 |
| Purity | Protein G affinity chromatography |
| Concentration (lot specific) | 1 mg/ml in 1X PBS, BSA free, sodium azide free |
| Recommended Applications | Immunofluorescence: 1-2ug/ml Immunohistochemistry (FFPE): 2-4ug/ml for 30 min at RT (1) |
| Domain / Region / Terminus | Cytoplasmic, cell surface and extracellular (secreted) |
| Research Area | Angiogenesis, Cardiovascular Disease, Vascular Biology |
| Shipping Type | Blue ice |
| Storage | ≤-20°C |
Description
Description
This mAb recognizes proteins of 19-22kDa (reducing) and 38kDa-44kDa (non-reducing), identified as various isoforms of Vascular Endothelial Growth Factor or Vascular Permeability Factor (VEGF/VPF). It is highly specific to VEGF, which is a homodimeric, disulfide-linked glycoprotein with a close homology to platelet derived growth factor (PDGF). There are multiple isoforms of VEGF containing 206-, 189-, 165-, and 121-amino acid residues. The smaller two isoforms, VEGF165 and VEGF121, are secreted proteins and act as diffusible agents, whereas the larger two remain cell associated. VEGF/VPF plays an important role in angiogenesis, which promotes tumor progression and metastasis.
Storage
Store the VEGF antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Expiration:
12 months from the date of shipment when stored properly.