Anti-VEGF Receptor 1 Antibody

Product Description

Specifications

Size	20 µL, 100 µL
Estimated Lead Time	1-2 weeks
Species	Human, Mouse, Rat
Host Species	Rabbit
Accession Number	P17948
Gene Id	2321
Gene Symbols	FLT1
Protein Name / Synonyms	FLT1, FLT, FLT-1, VEGFR-1, VEGFR1, fms related tyrosine kinase 1
Isotype	IgG
Purity	Affinity purification
Buffers	PBS with 0.09% Sodium azide, 50% glycerol, pH 7.3
Recommended Applications	Western Blotting, IHC
Research Area	Angiogenesis, Cardiovascular Disease, Cancer, Inflammation, Vascular Biology
Shipping Type	Blue ice
Storage	-20°C

Description

Background

This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.

Dilutions

WB 1:500 - 1:2000; IHC 1:50 - 1:100

Format

Calculated MW

39kDa/41kDa/52- 82kDa/150kDa

Observed MW

151kDa

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 20-300 of human VEGF Receptor 1 (NP_001153392.1).

Modification

Unmodified

Storage

Store at -20°. Avoid freeze / thaw cycles.

Images

Western blot

Expiration:

12 months from the date of shipment when stored properly.

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