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Anti-WT1 Antibody, Sodium Azide Free
Catalog #: 188-11436-SAF
Rabbit anti-Human Recombinant WT1 Antibody [Sodium Azide Free]
Product Description
Specifications
| Size | 100 µg |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Specificity | Other species not tested. |
| Host Species | Rabbit |
| Accession Number | P19544 |
| Gene Id | 7490 |
| Gene Symbols | WT1 |
| Protein Name / Synonyms | Wilms tumor protein (WT33) |
| Immunogen | A recombinant protein was used as the immunogen for the WT1 antibody. |
| Isotype | IgG, Kappa |
| Purity | Protein A affinity chromatography |
| Concentration (lot specific) | 1 mg/ml in 1X PBS, BSA free, sodium azide free |
| Recommended Applications | Immunofluorescence: 0.5-1ug/ml Immunohistochemistry (FFPE): 0.5-1ug/ml for 30 min at RT (1) |
| Domain / Region / Terminus | Cytoplasmic, membranous |
| Research Area | Cardiovascular Disease, Cancer |
| Shipping Type | Blue ice |
| Storage | ≤-20°C |
Description
Description
Wilms tumor is associated with mutations of WT1, a zinc-finger transcription factor that is essential for the development of the metanephric kidney and the urogenital system. The gene is normally expressed in fetal kidney and mesothelium, and its expression has been suggested as a marker for Wilms tumor and mesothelioma. WT1 protein has been identified in proliferative mesothelial cells, malignant mesothelioma, ovarian carcinoma, gonadoblastoma, nephroblastoma, and desmoplastic small round cell tumor. Lung adenocarcinomas rarely stain positive with this antibody. WT1 protein expression in mesothelial cells has become a reliable marker for the diagnosis of mesotheliomas.
Storage
Store the recombinant WT1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Expiration:
12 months from the date of shipment when stored properly.