Anti-YLAT2 (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q92536\|NP_003974.3
Gene Id	9057
Gene Symbols	SLC7A6
Protein Name / Synonyms	Y+L amino acid transporter 2, Cationic amino acid transporter, y+ system, Solute carrier family 7 member 6, y(+)L-type amino acid transporter 2, Y+LAT2, y+LAT-2, SLC7A6 (HGNC:11064)
Clonality	Polyclonal
Clone	RB26528
Isotype	Kappa, Rabbit
Recommended Applications	Western Blotting, FC
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This protein involved in the sodium-independent uptake of dibasic amino acids and sodium-dependent uptake of some neutral amino acids. It requires co-expression with SLC3A2/4F2hc to mediate the uptake of arginine, leucine and glutamine. It also acts as an arginine/glutamine exchanger, following an antiport mechanism for amino acid transport, influencing arginine release in exchange for extracellular amino acids. It plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine. It involved in the transport of L-arginine in monocytes and reduces uptake of ornithine in retinal pigment epithelial (RPE) cells.

Other Information

NCBI Accession #

NP_001070253.1;NP_003974.3

Antigen Type

Synthetic Peptide

Format

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Calculated Molecular Weight (Da)

56828

Antigen Source

Human

Images

WB (1:1000)

Western blot analysis of YLAT2 Antibody (C-term) (Cat. #102-26622) in HepG2 cell line lysates (35ug/lane).YLAT2 (arrow) was detected using the purified Pab.

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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