Anti-Zebrafish park7 (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Zebrafish
Host Species	Rabbit
Accession Number	Q5XJ36
Gene Id	449674
Gene Symbols	PARK7
Protein Name / Synonyms	Zebrafish DANRE park7 (C-term)
Clonality	Polyclonal
Preparation	This DANRE park7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 120-149 amino acids from the C-terminal region of DANRE park7.
Concentration (lot specific)	0.500 mg/ml
Recommended Applications	Western Blotting
Research Area	Neuroscience, Inflammation, Autophagy
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Protects cells against oxidative stress and cell death. May act as an atypical peroxiredoxin-like peroxidase that scavenges hydrogen peroxide. Following removal of a C-terminal peptide, displays protease activity and enhanced cytoprotective action against oxidative stress-induced apoptosis. Binds to a number of mRNAs containing multiple copies of GG or CC motifs and partially inhibits their translation but dissociates following oxidative stress. Required for correct mitochondrial morphology and function and for autophagy of dysfunctional mitochondria. Regulates astrocyte inflammatory responses. Acts as a positive regulator of androgen receptor-dependent transcription. Prevents aggregation of SNCA. Plays a role in fertilization. Has no proteolytic activity. Has cell-growth promoting activity and transforming activity. May function as a redox-sensitive chaperone (By similarity). Protects dopaminergic neurons against cell death arising from oxidative stress and proteasome inhibition, probably by a TP53/p53-dependent mechanism.

Specificity

Other Names

park7;dj1; Protein DJ-1; Protein DJ-1; Parkinson disease protein 7 homolog

NCBI Accession #

NP_001005938.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

19764

Recommended Dilutions

WB: 1:1000

DANRE park7 Antibody (C-term) (Cat# 102-18506) western blot analysis in zebra fish brain and muscle tissue lysates (35ug/lane).This demonstrates the DANRE park7 antibody detected the DANRE park7 protein (arrow).

Antigen Source

Zebrafish

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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