Anti-Zebrafish sh3bp4a (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Zebrafish
Host Species	Rabbit
Accession Number	Q1LVQ2
Gene Id	403082
Gene Symbols	sh3bp4a
Protein Name / Synonyms	SH3 domain-binding protein 4-A, sh3bp4a, sh3bp4
Clonality	Polyclonal
Clone	RB52023
Isotype	Kappa, Rabbit
Recommended Applications	Western Blotting
Research Area	Neuroscience, Autophagy
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Possible role in regulating endocytosis of the transferrin receptor at the plasma membrane. Alternatively, may function as a negative regulator of the amino acid-induced TOR signaling by inhibiting the formation of active Rag GTPase complexes. Preferentially binds inactive Rag GTPase complexes and prevents their interaction with the mTORC1 complex inhibiting its relocalization to lysosomes and its activation. Thereby, may indirectly regulate cell growth, proliferation and autophagy (By similarity).

Other Information

Format

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Calculated Molecular Weight (Da)

108453

Antigen Source

Human

Images

WB (1:1000)

Western blot analysis of lysate from ZF4 cell line, using DANRE sh3bp4a Antibody (N-term)(Cat. #102-24264). 102-24264 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20ug.

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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