Anti-ZRANB1 (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human, Mouse
Host Species	Rabbit
Accession Number	Q9UGI0
Gene Id	54764
Gene Symbols	ZRANB1
Protein Name / Synonyms	ZRANB1 (C-term)
Clonality	Polyclonal
Preparation	This ZRANB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 665-692 amino acids from the C-terminal region of human ZRANB1.
Concentration (lot specific)	0.500 mg/ml
Recommended Applications	Western Blotting, IHC-P
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

ZRANB1 is a positive regulator of the Wnt signaling pathway that specifically cleaves 'Lys-63'-linked ubiquitin chains. It acts by deubiquitinating APC protein, a negative regulator of Wnt-mediated transcription and may also modulate TNF-alpha signaling.

Specificity

Predicted Reactivity

Bovine

Other Names

ZRANB1; TRABID; Ubiquitin thioesterase ZRANB1; TRAF-binding domain-containing protein; Zinc finger Ran-binding domain-containing protein 1

NCBI Accession #

NP_060050.2

Other Accession #

Q7M760; A6QP16

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

80967

Recommended Dilutions

WB: 1:1000; IHC: 1:50-100

	Western blot analysis of ZRANB1 Antibody (C-term) (Cat# 102-18411) in K562 cell line lysates (35ug/lane). ZRANB1 (arrow) was detected using the purified Pab.
	Western blot analysis of ZRANB1 Antibody (C-term) (Cat# 102-18411) in mouse cerebellum tissue lysates (35ug/lane). ZRANB1 (arrow) was detected using the purified Pab.
	ZRANB1 Antibody (C-term) (Cat# 102-18411) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ZRANB1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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