Carboxyl Mono Mag (1 µm) are hydrophilic magnetic beads with carboxylic acid groups. These surface groups allow covalent amide bond formation to proteins/peptides via primary amine (NH2) groups. Oligonucleotides, antibodies or other ligands with amine groups can be easily coupled to the beads. Activation through carbodimide is required. With their large surface area, uniform size, narrow size distribution and unique surface coating, Carboxyl Mono Mag (1 µm) exhibit high binding capacity and low non-specific binding of protein or nucleic acids. Their compact structure also ensures faster magnetic separation than Hi-Sur Mag Beads (1 µm).