Rabbit Anti-EDNRB (C-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse |
| Host Species | Rabbit |
| Accession Number | P24530 |
| Gene Id | 1910 |
| Gene Symbols | EDNRB |
| Protein Name / Synonyms | EDNRB (C-term) |
| Clonality | Polyclonal |
| Preparation | This EDN_ antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 409-439 amino acids from the C-terminal region of human EDN_. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting, IHC-P, IF, FC |
| Research Area | Cardiovascular Disease |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
EDNRB is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene.
Specificity
Predicted Reactivity
Rat, Bovine, Pig, Rabbit
Other Names
EDNRB; ETRB; Endothelin B receptor; Endothelin receptor non-selective type
NCBI Accession #
NP_000106.1;NP_001116131.1;NP_001188326.1;NP_003982.1
Other Accession #
P21451; Q9N0W7; P35463; P48302; P28088
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
49644
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50; IF: 1:10-50; FC: 1:10-50
 | Western blot analysis of EDNRB Antibody (C-term) (Cat# 102-16939) in mouse cerebellum tissue lysates (35ug/lane). EDNRB (arrow) was detected using the purified Pab. |
 | EDNRB Antibody (C-term) (Cat# 102-16939)immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of EDNRB Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
 | Confocal immunofluorescent analysis of EDNRB Antibody (C-term)(Cat# 102-16939) with 293 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). |
 | EDNRB Antibody (C-term) (Cat# 102-16939) flow cytometric analysis of MDA-MB435 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.