Goat Anti-Human SNAP-25 (C-term)
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Anti-SNAP-25 (C-term) Antibody
| Size | 0.1 mg |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Specificity | This product detects an epitope within the C-terminal (CT) of human synaptosomal-associated protein, 25kD (SNAP-25). SNAP-25 is a presynaptic plasma membrane protein which is essential for Ca2+-regulated exocytosis of neurotransmitters. SNAP-25 has been shown to bind to and negatively modulate Ca2+ channels, increasing the speed of neurotransmitter release. SNAP-25 is expressed by neurons and neuroendocrine cells as two predominant isoforms; SNAP-25a and SNAP-25b. SNAP-25a is expressed early in development, whereas SNAP-25b expression is linked to synaptogenesis. This product is expected to recognize both isoforms. SNAP-25 may be a possible therapeutic treatment for sufferers of hyperactivity disorders, whilst SNAP-25 based peptides may be a possible treatment for involuntary muscle spasms. |
| Host Species | Goat |
| Protein Name / Synonyms | SNAP-25 |
| Preparation | Antisera to human SNAP-25 were raised by repeated immunisations of goats with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography. |
| Concentration (lot specific) | IgG concentration 0.5 mg/ml |
| Recommended Applications | ELISA (dilution: 0.01, 0.03ug/ml), Western Blotting |
| Research Area | Neuroscience |
| Shipping Type | Blue ice |
| Storage | -20°C |
This product detects a band of approximately 22kDa in human and mouse brain lysates. A minimum incubation time of 1 hour is recommended with this antibody.
Store at +4 °C or at -20 °C if preferred.
This product should be stored undiluted.
Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Antisera to human SNAP-25 were raised by repeated immunisations of goats with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
| 0.02% | Sodium Azide |
| 0.5% | Bovine Serum Albumin |
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Anti-SNAP-25 (C-term) Antibody