Mouse anti-Human/Monkey/Dog TLR2 Antibody (Toll Like Receptor 2)

Mouse anti-Human/Monkey/Dog TLR2 Antibody (Toll Like Receptor 2)

$198.00
188-10715-1
+

Antigen Information

Accession Number:
  • O60603
Gene ID:
  • 7097
Gene Symbols:
  • TIL4
  • TLR2
Protein Name & Synonyms:
Toll-like receptor 2 (Toll/interleukin-1 receptor-like protein 4) (CD antigen CD282)
Target Species:
  • Canine (dog)
  • Human
  • Non-human Primates

Antibody Specifications

Applications:
Functional Activity (Order SAF formulation)
Flow Cytometry: 0.5-1ug/million cells in 0.1ml
Immunofluorescence: 1-2ug/ml
Immunohistochemistry (FFPE): 0.5-1ug/ml for 30 min at RT (1)
Concentration:
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Domain/Region/Terminus:
Cell surface
Host Species:
Mouse
Preparation:
Recombinant human protein was used as the immunogen for the TLR2 antibody.
Purity:
Protein G affinity chromatography
Species Reactivity:
Human, Monkey and Dog. Other species not tested.

Description

This mAb reacts with human Toll-like receptor 2 (TLR2). It is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB.

Storage

The antibody is stable for at least 1 year from the date of receipt when stored at -20°C to -70°C. Reconstituted antibody can also be aliquotted and stored at 4°C for 1 month or at -20°C to -70°C in a manual defrost freezer for many months without detectable loss activity. Please avoid freeze-thaw cycles.

No posts found

Write A Review
U.S. Non-U.S.

Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.