Neurophysin II is a carrier protein and is cleaved from a precursor also consisting of vasopressin and copeptin. Neurophysin II specifically binds vasopressin. Vasopressin has a direct antidiuretic action on the kidney, and it also causes vasoconstriction of the peripheral vessels. Neurophysin II is also known as a stimulator of prolactin secretion, and can be associated with neurohypophyseal diabetes insipidus.

Standard, biotinylated peptide, and positive control should be stored at -20°C after arrival. Avoid multiple freeze-thaws. The remaining kit components may be stored at 4°C. Opened microplate wells and antibody (Item N) may be stored for up to 1 month at 2° to 8°C. Return unused wells to the pouch containing desiccant pack and reseal along entire edge.