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Insulin-Like Growth Factor 1 Des (1-3), Human Recombinant

Catalog #: 228-10835

Product Description

Specifications

Size100 µg, 1000 µg
Estimated Lead Time2-3 weeks
SpeciesHuman
Accession Number
P01343
Protein Name / Synonyms
Somatomedin C, IGF-I, IGFI, IGF1, IGF-IA, Mechano growth factor, MGF, Des(1-3), Des1-3, Des 1-3, Des (1-3), IGF-1 (4-70).
Expressed Region
The sequence of the first five N-terminal amino acids was determined and was found to be Thr-Leu-Cys-Gly-Ala.
Expression SystemE. coli
Purity
Greater than 95.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
Format
Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation
The protein was lyophilized after extensive dialysis against 50mM acetic acid buffer.
Activity
The ED50, calculated by the dose-dependant proliferation of murine BALBC 3T3 cells (measured by 3H-thymidine uptake) is <, 1ng/ml, corresponding to a specific activity of 1,000,000units/mg. For most in-vitro applications, IGF-I des1-3 exerts its biologi
Research AreaCancer, Inflammation
Shipping TypeAmbient temperature
Storage-20°C

Description

Description

IGF-I Des(1-3) Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 67 amino acids (aa 4-70) and having a molecular mass of 7372 Dalton. IGF-1 Des1-3 is purified by proprietary chromatographic techniques.

Stability & Storage

Storage/Stability
Lyophilized IGF-I des(1-3) although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IGF1 des-1-3 should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.