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ISO 13485:2016 cGMP

Macrophage-Colony Stimulating Factor, Mouse Recombinant

Catalog #: 228-11066

Product Description

Specifications

Size10 µg, 1000 µg
Estimated Lead Time2-3 weeks
SpeciesMouse
Accession Number
P07141
Gene Id
12977
Protein Name / Synonyms
CSF-1, Lanimostim, MCSF, M-CSF.
Expressed Region
MKEVSEHCSH MIGNGHLKVL QQLIDSQMET SCQIAFEFVD QEQLDDPVCY LKKAFFLVQD IIDETMRFKD NTPNANATER LQELSNNLNS CFTKDYEEQN KACVRTFHET PLQLLEKIKN FFNETKNLLE KDWNIFTKNC NNSFAKCSSR DVVTKP.
Expression SystemE. coli
Purity
Greater than 98.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
Format
Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation
The protein was lyophilized with 0.5xPBS, pH 8.0.
Activity
The ED50, as calculated by the dose-dependant stimulation of the proliferation of murine M-NFS-60 indicator cells is typically 1.1-1.6ng/ml corresponding to 909,090-625,000 U/mg.
Research AreaInflammation
Shipping TypeAmbient temperature
Storage-20°C

Description

Description

Macrophage Colony Stimulating Factor Mouse Recombinant produced in E.coli is a disulfide linked homodimer, non-glycosylated, polypeptide chain containing 2 x 156 amino acids and having a total molecular mass of 36.4 KD.MCSF is purified by proprietary chromatographic techniques.

Stability & Storage

Storage/Stability
Lyophilized M-CSF although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution MCSF should be stored at 4°C between 2-7 days and for future use below -18°C.Please prevent freeze-thaw cycles.