This FGA antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 420-448 amino acids from the N-terminal region of human FGA.
Clonality
Monoclonal
Species
Human, Mouse
Introduction
The protein encoded by this gene is the alpha component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. Alternative splicing results in two isoforms which vary in the carboxy-terminus. [provided by RefSeq].
Specificity
Other Names
FGA; Fibrinogen alpha chain; Fibrinopeptide A
NCBI Accession #
NP_000499.1;NP_068657.1
Other Accession #
NP_000499.1
Format
Type
Mouse Monoclonal Antibody (Mab)
Calculated Molecular Weight (Da)
94973
Recommended Dilutions
WB: 1:100-500
FGA Antibody (N-term) (Cat# 102-10275) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the FGA(N-term) antibody detected the FGA(N-term) protein (arrow).
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.
