Mouse Anti-Human BLNK (Ascites)

Mouse Anti-Human BLNK (Ascites) Antibody, 0.1 ml
$334.00
In stock
Code:
102-10302
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+

Product Description

Specifications

Size 0.1 ml
Protein Name / Synonyms BLNK (Ascites)
Accession Number Q8WV28
Gene Symbols BLNK
Gene Id 29760
Preparation This BLNK antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 150-178 amino acids from human BLNK.
Clonality Monoclonal
Species Human

Introduction

This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Specificity

Other Names
BLNK; BASH; SLP65; B-cell linker protein; B-cell adapter containing a SH2 domain protein; B-cell adapter containing a Src homology 2 domain protein; Cytoplasmic adapter protein; Src homology 2 domain-containing leukocyte protein of 65 kDa
NCBI Accession #
NP_001107566.1;NP_001245369.1;NP_037446.1
Other Accession #
NP_001107566.1

Format

Type
Mouse Monoclonal Antibody (Mab)
Calculated Molecular Weight (Da)
50466
Recommended Dilutions
WB: 1:500-8000
BLNK Antibody (Cat# 102-10302) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the BLNK antibody detected the BLNK protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.
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