This product recognizes complement component 7 (C7), a 110 kDa glycoprotein present in the blood serum. The factor I domain of C7 binds the C terminus of the C5 alpha-chain, acting as a membrane anchor. This enables the assembly of the complement membrane attack complex (MAC) and consequent complement lytic activity. C7 deficiency is associated with increased susceptibility to recurrent infections, in particular by Neisseria meningitides.

Note that This product does not recognize membrane bound complement membrane attack complex.

This product inhibits lysis of sensitised sheep erythrocytes.

IgG concentration 1.0 mg/ml

Storage/Stability

Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:

Purified IgG - liquid

Formulation:

Borate buffered saline

Format Type:

Purified

Preparation

Immunogen:

Purified human C7

Preservative:

0.1% Sodium Azide (NaN₃)

Expiration:

12 months from the date of shipment when stored properly.

IgG concentration 1.0 mg/ml

Storage/Stability

Format

Supplied as:

Purified IgG - liquid

Formulation:

Borate buffered saline

Format Type:

Purified

Preparation

Immunogen:

Purified human C7

Preservative:

0.1% Sodium Azide (NaN₃)

Expiration:

12 months from the date of shipment when stored properly.

Size	0.1 mg
Estimated Lead Time	1-2 weeks
Species	Human
Specificity	This product recognizes complement component 7 (C7), a 110 kDa glycoprotein present in the blood serum. The factor I domain of C7 binds the C terminus of the C5 alpha-chain, acting as a membrane anchor. This enables the assembly of the complement membrane attack complex (MAC) and consequent complement lytic activity. C7 deficiency is associated with increased susceptibility to recurrent infections, in particular by Neisseria meningitides. Note that This product does not recognize membrane bound complement membrane attack complex. This product inhibits lysis of sensitised sheep erythrocytes.
Host Species	Mouse
Protein Name / Synonyms	C7
Concentration (lot specific)	IgG concentration 1.0 mg/ml
Recommended Applications	ELISA, Functional Assays, Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Size	0.1 mg
Estimated Lead Time	1-2 weeks
Species	Human
Specificity	This product recognizes complement component 7 (C7), a 110 kDa glycoprotein present in the blood serum. The factor I domain of C7 binds the C terminus of the C5 alpha-chain, acting as a membrane anchor. This enables the assembly of the complement membrane attack complex (MAC) and consequent complement lytic activity. C7 deficiency is associated with increased susceptibility to recurrent infections, in particular by Neisseria meningitides. Note that This product does not recognize membrane bound complement membrane attack complex. This product inhibits lysis of sensitised sheep erythrocytes.
Host Species	Mouse
Protein Name / Synonyms	C7
Concentration (lot specific)	IgG concentration 1.0 mg/ml
Recommended Applications	ELISA, Functional Assays, Western Blotting
Shipping Type	Blue ice
Storage	-20°C

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