This GJC2 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 53-78 amino acids from the N-terminal region of human GJC2.
GJC2 is a gap junction protein. Gap junction proteins are members of a large family of homologous connexins and comprise 4 transmembrane, 2 extracellular, and 3 cytoplasmic domains. This gene plays a key role in central myelination and is involved in peripheral myelination in humans. Defects in this gene are the cause of autosomal recessive Pelizaeus-Merzbacher-like disease-1.
Mouse, Rat, Zebrafish, Bovine, Chicken, Hamster, Pig, Xenopus
GJC2; GJA12; Gap junction gamma-2 protein; Connexin-46.6; Connexin-47; Gap junction alpha-12 protein