Mouse Anti-Human IL10(Ascites) Antibody, 0.1 ml
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Product Description
Specifications
| Size | 0.1 mL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Accession Number | P22301 |
| Gene Id | 3586 |
| Gene Symbols | IL10 |
| Protein Name / Synonyms | IL10(Ascites) |
| Clonality | Monoclonal |
| Preparation | This IL10 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 27-53 amino acids from human IL10. |
| Recommended Applications | Western Blotting |
| Research Area | Angiogenesis, Inflammation, Autophagy |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. [provided by RefSeq].
Specificity
Predicted Reactivity
EBV, Monkey
Other Names
IL10; Interleukin-10; Cytokine synthesis inhibitory factor
NCBI Accession #
NP_000563.1
Other Accession #
P79338; P03180; NP_000563.1
Format
Type
Mouse Monoclonal Antibody (Mab)
Calculated Molecular Weight (Da)
20517
Recommended Dilutions
WB: 1:100-400
 | IL10 Antibody (Cat# 102-10325) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the IL10 antibody detected the IL10 protein (arrow). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.