Mouse Anti-Human MC1R (Center)

Mouse Anti-Human MC1R (Center) Antibody, 400 ul
In stock

Product Description


Size 400 µl
Protein Name / Synonyms MC1R (Center)
Accession Number Q01726
Gene Symbols MC1R
Gene Id 4157
Concentration (lot specific) 2.0 mg/ml
Preparation This MC1R antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 205-232 amino acids from the Central region of human MC1R.
Clonality Monoclonal
Species Human


This intronless gene encodes the receptor protein for melanocyte-stimulating hormone (MSH). The encoded protein, a seven pass transmembrane G protein coupled receptor, controls melanogenesis. Two types of melanin exist: red pheomelanin and black eumelanin. Gene mutations that lead to a loss in function are associated with increased pheomelanin production, which leads to lighter skin and hair color. Eumelanin is photoprotective but pheomelanin may contribute to UV-induced skin damage by generating free radicals upon UV radiation. Binding of MSH to its receptor activates the receptor and stimulates eumelanin synthesis. This receptor is a major determining factor in sun sensitivity and is a genetic risk factor for melanoma and non-melanoma skin cancer. Over 30 variant alleles have been identified which correlate with skin and hair color, providing evidence that this gene is an important component in determining normal human pigment variation. [provided by RefSeq].


Other Names
MC1R; MSHR; Melanocyte-stimulating hormone receptor; Melanocortin receptor 1
NCBI Accession #
Other Accession #


Mouse Monoclonal Antibody (Mab)
Calculated Molecular Weight (Da)
Recommended Dilutions
WB: 1:100-250
MC1R Antibody (Center)(Cat# 102-10333) western blot analysis in A375 cell line lysates (35ug/lane).This demonstrates the MC1R antibody detected the MC1R protein (arrow).

Antigen Source



2-8°C (short-term); -20°C (long-term)
12 months from the date of shipment when stored properly.
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