Purified His-tagged NFKBIA protein was used to produced this monoclonal antibody.
Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.
NFKBIA;IKBA; MAD3; NFKBI; NF-kappa-B inhibitor alpha; NF-kappa-B inhibitor alpha; I-kappa-B-alpha; NF-kappa-B inhibitor alpha; Major histocompatibility complex enhancer-binding protein MAD3
NCBI Accession #
Mouse Monoclonal Antibody (Mab)
Calculated Molecular Weight (Da)
NFKBIA Antibody (Cat# 102-10424) western blot analysis in Hela,mouse NIH/3T3 cell line lysates (35ug/lane).This demonstrates the NFKBIA antibody detected the NFKBIA protein (arrow).
2-8°C (short-term); -20°C (long-term)
12 months from the date of shipment when stored properly.