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Antigen Information
Protein Name & Synonyms:
p53
Target Species:
- Human
Antibody Specifications
Applications:
Immunohistology - Frozen, ELISA (dilution: , 1/1000), Immunoprecipitation, Immunohistology - Paraffin, Western Blotting
Concentration:
IgG concentration 1.0 mg/ml
Species Reactivity:
Human, This antibody is reported to cross react with bovine, equine and feline Does not react with mouse or rat p53
Specificity
This product recognizes the human p53 tumour suppressor protein, binding to both wild type and mutant forms. p53 is important in multicellular organisms, where it regulates the cell cycle and thus functions as a tumor suppressor that is involved in preventing cancer.
The antibody recognizes an epitope at the N-terminal end of p53 between amino acids 20-25.
The antibody recognizes an epitope at the N-terminal end of p53 between amino acids 20-25.
Storage/Stability
Store at +4 °C or at -20 °C if preferred.
This product should be stored undiluted.
Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Format
Supplied as:
Purified IgG - liquid
Formulation:
Phosphate buffered saline
Format Type:
Purified
Preparation
Immunogen:
Recombinant human p53
Preservative:
| 0.09% | Sodium Azide |
This product
Spleen cells from immunised BALB/c mice were fused with cells of the mouse X63Ag8.653 myeloma cell line.
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Usage
This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.
