Mouse Anti-Human STAT3 Antibody, 400 ul
$334.00
In stock
Code:
102-10514
-
+

Product Description

Specifications

Size 400 µl
Protein Name / Synonyms STAT3
Accession Number P40763
Gene Symbols STAT3
Gene Id 6774
Concentration (lot specific) 0.5 mg/ml
Preparation This STAT3 antibody is generated from a mouse immunized with a recombinant protein from human.
Clonality Monoclonal
Species Human

Introduction

Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)- responsive elements identified in the promoters of various acute- phase protein genes. Activated by IL31 through IL31RA. Cytoplasmic STAT3 represses macroautophagy by inhibiting EIF2AK2/PKR activity. Plays an important role in host defense in methicillin-resistant S.aureus lung infection by regulating the expression of the antimicrobial lectin REG3G (By similarity).

Specificity

Predicted Reactivity
Mouse, Rat, Pig
Other Names
Signal transducer and activator of transcription 3, Acute-phase response factor, STAT3, APRF
Other Accession #
P52631; Q19S50; P42227

Format

Type
Purified Mouse Monoclonal Antibody (Mab)
Calculated Molecular Weight (Da)
88068
Recommended Dilutions
WB: 1:1000
Western blot analysis of lysates from CEM, Hela cell line (from left to right), using Stat3 Antibody(Cat# 102-10514). 102-10514 was diluted at 1:1000 at each lane. A goat anti-mouse IgG H&L(HRP) at 1:3000 dilution was used as the secondary antibody. Lysates at 35ug per lane.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.
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