This TLE4 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 262-290 amino acids from the Central region of human TLE4.
Clonality
Monoclonal
Species
Human
Introduction
Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by PAX5, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES (By similarity).
Specificity
Predicted Reactivity
Mouse, Rat
Other Names
TLE4; KIAA1261; Transducin-like enhancer protein 4
NCBI Accession #
NP_008936.2
Other Accession #
Q07141; Q62441; NP_008936.2
Format
Type
Mouse Monoclonal Antibody (Mab)
Calculated Molecular Weight (Da)
83755
Recommended Dilutions
WB: 1:100-3200
TLE4 Antibody (Center) (Cat# 102-10244) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the TLE4 antibody detected the TLE4 protein (arrow).
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.
