Mouse Anti-Human TP53 (N-term)

Mouse Anti-Human TP53 (N-term) Antibody, 400 ul
In stock

Product Description


Size 400 µl
Protein Name / Synonyms TP53 (N-term)
Accession Number P04637
Gene Symbols TP53
Gene Id 7157
Concentration (lot specific) 0.460 mg/ml
Preparation Purified His-tagged TP53 protein was used to produced this monoclonal antibody.
Clonality Monoclonal
Species Human


Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-mediated apoptosis.


Other Names
TP53;P53; Cellular tumor antigen p53; Cellular tumor antigen p53; Antigen NY-CO-13; Cellular tumor antigen p53; Phosphoprotein p53; Cellular tumor antigen p53; Tumor suppressor p53
NCBI Accession #


Mouse Monoclonal Antibody (Mab)
Calculated Molecular Weight (Da)
Recommended Dilutions
WB: 1:1000
TP53 Antibody (N-term) (Cat# 102-10471) western blot analysis in HT29 cell line lysates (35ug/lane).This demonstrates the TP53 antibody detected the TP53 protein (arrow).

Antigen Source



2-8°C (short-term); -20°C (long-term)
12 months from the date of shipment when stored properly.
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