Mouse Anti-Human VRK1 (Center)(Ascites) Antibody, 100ul
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Product Description
Specifications
| Size | 100 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Accession Number | Q99986 |
| Gene Id | 7443 |
| Gene Symbols | VRK1 |
| Protein Name / Synonyms | VRK1 (Center)(Ascites) |
| Clonality | Monoclonal |
| Preparation | Purified His-tagged VRK1 protein was used to produced this monoclonal antibody. |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
Serine/threonine kinase involved in Golgi disassembly during the cell cycle: following phosphorylation by PLK3 during mitosis, required to induce Golgi fragmentation. Acts by mediating phosphorylation of downstream target protein. Phosphorylates 'Thr-18' of p53/TP53 and may thereby prevent the interaction between p53/TP53 and MDM2. Phosphorylates casein and histone H3. Phosphorylates BANF1: disrupts its ability to bind DNA, reduces its binding to LEM domain-containing proteins and causes its relocalization from the nucleus to the cytoplasm.
Specificity
Other Names
VRK1;Serine/threonine-protein kinase VRK1; Serine/threonine-protein kinase VRK1; Vaccinia-related kinase 1
NCBI Accession #
NP_003375.1
Format
Type
Mouse Monoclonal Antibody (Mab)
Calculated Molecular Weight (Da)
45476
Recommended Dilutions
WB: 1:5000
 | VRK1 Antibody (Center)(Cat# 102-10453) western blot analysis in Hela,HL-60 cell line lysates (35ug/lane).This demonstrates the VRK1 antibody detected the VRK1 protein (arrow). |
Antigen Source
Human
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.