This A2M antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 1162-1192 amino acids from the C-terminal region of human A2M.
Clonality
Monoclonal
Species
Mouse
Introduction
Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. [provided by RefSeq].
Specificity
Other Names
A2M; CPAMD5; Alpha-2-macroglobulin; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5
NCBI Accession #
NP_000005.2
Other Accession #
NP_000005
Format
Type
Mouse Monoclonal Antibody (Mab)
Calculated Molecular Weight (Da)
163291
Recommended Dilutions
WB: 1:100-200
A2M Antibody (C-term)(Ascites)(Cat# 102-10330) western blot analysis in mouse Liver tissue lysates (35ug/lane).This demonstrates the A2M antibody detected the A2M protein (arrow).
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.