Mouse Anti-Mouse GNAS (Ascites)

Mouse Anti-Mouse GNAS (Ascites) Antibody, 0.1 ml
In stock

Product Description


Size 0.1 ml
Protein Name / Synonyms GNAS (Ascites)
Accession Number Q5FWY2
Preparation This GNAS antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 287-315 amino acids from human GNAS.
Clonality Monoclonal
Species Mouse


Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The Gs protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase in response to beta-adrenergic stimuli. Alternative splicing of downstream exons of the GNAS gene is observed, which results in different forms of the stimulatory G protein alpha subunit, a key element of the classical signal transduction pathway linking receptor-ligand interactions with the activation of adenylyl cyclase and a variety of cellular reponses. Multiple transcript variants have been found for this gene, but the full-length nature and/or biological validity of some variants have not been determined. Mutations in this gene result in pseudohypoparathyroidism type 1a, pseudohypoparathyroidism type 1b, Albright hereditary osteodystrophy, pseudopseudohypoparathyroidism, McCune-Albright syndrome, progressive osseus heteroplasia, polyostotic fibrous dysplasia of bone, and some pituitary tumors.


Predicted Reactivity
Human, Rat, Bovine, Humanamster, Pig
Other Names
GNAS complex locus;GNAS;
Other Accession #
P29797; Q8R4A8; P63095; P63094; P63092; P04896; Q63803; Q6R0H7; Q5JWF2


Mouse Monoclonal Antibody (Mab)
Recommended Dilutions
WB: 1:300
GNAS Antibody(Ascites)(Cat# 102-10353) western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the GNAS antibody detected the GNAS protein (arrow).

Antigen Source



2-8°C (short-term); -20°C (long-term)
12 months from the date of shipment when stored properly.
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