Methicillin-resistant Staphylococcus aureus (MRSA) is a major pathogen responsible for serious hospital infections worldwide. These bacteria are resistant to all beta-lactam antibiotics due to the production of an additional penicillin binding protein, the PBP2a (about 75kDa) encoded by the mecA gene, which shows low affinity for this class of antibiotics. According to the resistant and sensitive ability of the bacteria to antibiotics, two main groups are classified: MRSA and MSSA (Methicillinsensitive Staphylococcus aureus).

The antibody is stable for at least 1 year from the date of receipt when stored at -20°C to -70°C. Reconstituted antibody can also be aliquotted and stored at 4°C for 1 month or at -20°C to -70°C in a manual defrost freezer for many months without detectable loss activity. Please avoid freeze-thaw cycles.

This antibody was selected for its ability to specifically detect PBP2a from MRSA. The antibody has ability to distinguish both MRSA and MSSA in tested assays; in Western Blot analysis, this antibody did not produce a band for any bacterial cell lysates from MSSA. This antibody showed no cross-reactivity with other tested bacterial proteins.