Mouse Anti-PIN1 Antibody, 400ul
$334.00
In stock
Code:
102-10434
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+

Product Description

Specifications

Size 400 µl
Protein Name / Synonyms PIN1
Accession Number Q13526
Gene Symbols PIN1
Gene Id 5300
Concentration (lot specific) 0.350 mg/ml
Preparation Purified His-tagged PIN1 protein was used to produced this monoclonal antibody.
Clonality Monoclonal
Species Human, Mouse, Rat

Introduction

Essential PPIase that regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity. Displays a preference for an acidic residue N-terminal to the isomerized proline bond. Catalyzes pSer/Thr-Pro cis/trans isomerizations. Down-regulates kinase activity of BTK. Can transactivate multiple oncogenes and induce centrosome amplification, chromosome instability and cell transformation. Required for the efficient dephosphorylation and recycling of RAF1 after mitogen activation.

Specificity

Other Names
PIN1;Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1; Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1; Peptidyl-prolyl cis-trans isomerase Pin1; Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1; Rotamase Pin1
NCBI Accession #
NP_006212.1

Format

Type
Mouse Monoclonal Antibody (Mab)
Calculated Molecular Weight (Da)
18243
Recommended Dilutions
WB: 1:1000
PIN1 Antibody (Cat# 102-10434) western blot analysis in Hela,293,mouse NIH/3T3,PC-12,COS-7 cell line and mouse brain,rat brain tissue lysates (35ug/lane).This demonstrates the PIN1 antibody detected the PIN1 protein (arrow).

Antigen Source

Human

Storage/Stability

2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.
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